LSN2424100

Ligand id: 9121

Name: LSN2424100

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 74.44
Molecular weight 407.11
XLogP 6.82
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-fluoro-N-(1H-imidazol-2-ylmethyl)-N-(2-phenylphenyl)benzene-1-sulfonamide
Database Links
PubChem CID 121231398
Search Google for chemical match using the InChIKey PCDMCECXKAELMI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PCDMCECXKAELMI
Search UniChem for chemical match using the InChIKey PCDMCECXKAELMI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PCDMCECXKAELMI
Comments
LSN2424100 is a potent orexin receptor antagonist (OX2 selective) with potential antidepressant-like action [1]. Can be used as an experimental probe of OX2 receptor-mediated signaling.