3M-002

Ligand id: 9270

Name: 3M-002

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	2
Topological polar surface area	80.04
Molecular weight	243.08
XLogP	3.27
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine

IUPAC Name

2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine

Synonyms
CL-075 \| CL075

Synonyms

CL-075 | CL075

Database Links
ChEMBL Ligand	CHEMBL512901
GtoPdb PubChem SID	315661345
PubChem CID	10198719
RCSB PDB Ligand	L07
Search Google for chemical match using the InChIKey	NFYMGJSUKCDVJR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	NFYMGJSUKCDVJR
Search UniChem for chemical match using the InChIKey	NFYMGJSUKCDVJR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	NFYMGJSUKCDVJR

Comments
3M-002 is reported as a selective Toll-like receptor 8 agonist, which promotes TNF-α and IL-12 production from human PBMCs [1].

Comments

3M-002 is reported as a selective Toll-like receptor 8 agonist, which promotes TNF-α and IL-12 production from human PBMCs [1].