tolimidone

Ligand id: 9433

Name: tolimidone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 50.36
Molecular weight 203.08
XLogP 2.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-(3-methylphenoxy)-1H-pyrimidin-2-one
International Nonproprietary Names
INN number INN
4543 tolimidone
Synonyms
CP-26154 | MLR-1023
Database Links
ChEMBL Ligand CHEMBL8030
PubChem CID 39065
Search Google for chemical match using the InChIKey HJQILFPVRNHTIG-UHFFFAOYSA-N
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Comments
Tolimidone is a potent and selective allosteric activator of Lyn kinase [1]. It was developed for the treatment of type 2 diabetes.