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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|Ligand families/groups||Non-steroidal anti-inflammatory ligands|
|ATB-346 a novel, orally available, GI-sparing hydrogen sulfide (H2S)-releasing anti-inflammatory drug in preclinical development for melanoma  and in clinical trial in osteoarthritis (preclinical findings in ). Structurally it is a non-steroidal anti-inflammatory (naproxen) covalently linked to an H2S-releasing moiety. ATB-346 is therefore an H2S prodrug.
H2S-releasing anti-inflammatory drugs are in development for their potential anti-inflammatory, cytoprotective and chemopreventative properties [4,6-7,10-11].
|GtoPdb PubChem SID||336446920|
|Search Google for chemical match using the InChIKey||YCNMAPLPQYQJFC-UHFFFAOYSA-N|
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