PF-06840003

Ligand id: 9565

Name: PF-06840003

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 61.96
Molecular weight 232.06
XLogP 0.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
Synonyms
EOS200271 | PF06840003
Database Links
PubChem CID 23063810
Search Google for chemical match using the InChIKey MXKLDYKORJEOPR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MXKLDYKORJEOPR
Search UniChem for chemical match using the InChIKey MXKLDYKORJEOPR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MXKLDYKORJEOPR
Comments
PF-06840003 is a small molecule IDO1 inhibitor, designed as a cancer immunotherapeutic. It is claimed as compound 1 in patent WO2015173764 [1].