G1T28

Ligand id: 9626

Name: G1T28

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 91.21
Molecular weight 446.25
XLogP 2.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]spiro[7,8-dihydropyrazino[5,6]pyrrolo[1,2-d]pyrimidine-9,1'-cyclohexane]-6-one
Synonyms
trilaciclib (proposed INN)
Database Links
CAS Registry No. 1374743-00-6 (source: WHO INN record)
PubChem CID 68029831
Search Google for chemical match using the InChIKey PDGKHKMBHVFCMG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PDGKHKMBHVFCMG
Search UniChem for chemical match using the InChIKey PDGKHKMBHVFCMG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PDGKHKMBHVFCMG
Comments
G1T28 is an investigational short-acting CDK4/6 inhibitor being developed by G1 Therapeutics [2].