CFI-400945

Ligand id: 8063

Name: CFI-400945

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 79.48
Molecular weight 534.26
XLogP 6.64
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(1R)-2-{3-[(E)-2-(4-{[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl}phenyl)ethenyl]-1H-indazol-6-yl}-1-(3-methoxyphenyl)cyclopropane-1-carbaldehyde
Synonyms
CFI 400945 | CFI400945
Database Links
CAS Registry No. 1338800-06-8
PubChem CID 67978713
Search Google for chemical match using the InChIKey DADASRPKWOGKCU-IHKPOXLFSA-N
Search Google for chemicals with the same backbone DADASRPKWOGKCU
Search UniChem for chemical match using the InChIKey DADASRPKWOGKCU-IHKPOXLFSA-N
Search UniChem for chemicals with the same backbone DADASRPKWOGKCU
Comments
CFI-400945 is an investigational, selective inhibitor of polo-like kinase 4 (PLK4) [1-2].