protein arginine methyltransferase 7

Target id: 1258

Nomenclature: protein arginine methyltransferase 7

Abbreviated Name: PRMT7

Family: 2.1.1.- Protein arginine N-methyltransferases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for protein arginine methyltransferase 7 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - PRMT7 protein arginine methyltransferase 7
Mouse - - Prmt7 protein arginine N-methyltransferase 7
Rat - - Prmt7 protein arginine methyltransferase 7
Previous and Unofficial Names
[Myelin basic protein]-arginine N-methyltransferase PRMT7
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 2.1.1.125
EC Number: 2.1.1.126

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
DS-437 Hs Inhibition 5.2 pIC50 1
pIC50 5.2 (IC50 6x10-6 M) [1]

References

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1. Smil D, Eram MS, Li F, Kennedy S, Szewczyk MM, Brown PJ, Barsyte-Lovejoy D, Arrowsmith CH, Vedadi M, Schapira M. (2015) Discovery of a Dual PRMT5-PRMT7 Inhibitor. ACS Med Chem Lett6 (4): 408-12. [PMID:25893041]

How to cite this page

2.1.1.- Protein arginine N-methyltransferases: protein arginine methyltransferase 7 . Last modified on 13/08/2015. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1258.