Aminopeptidase A

Target id: 1559

Nomenclature: Aminopeptidase A

Family: M18: Aminopeptidase I

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Aminopeptidase A in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 485 2q36.1 DNPEP aspartyl aminopeptidase
Mouse - 475 1 C3-C4 Dnpep aspartyl aminopeptidase
Rat - 475 9q33 Dnpep aspartyl aminopeptidase
Previous and Unofficial Names
ASPEP | DAP | cytosolic aminopeptidase
Database Links
Specialist databases
MEROPS M18.002 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.11.21

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 9 [PMID: 1738140] Hs Inhibition 6.3 pKi 1
pKi 6.3 (Ki 5.1x10-7 M) [1]
Inhibitor Comments
As the source of the enzyme used to generate the Ki value for compound 9 is not clear from the referenced article, we have not specified species in the table above.

References

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1. Ocain TD, Rich DH. (1992) alpha-Keto amide inhibitors of aminopeptidases. J. Med. Chem.35 (3): 451-6. [PMID:1738140]

How to cite this page

M18: Aminopeptidase I: Aminopeptidase A. Last modified on 29/07/2015. Accessed on 24/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1559.