Endoplasmic reticulum aminopeptidase 2

Target id: 1567

Nomenclature: Endoplasmic reticulum aminopeptidase 2

Family: M1: Aminopeptidase N

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Endoplasmic reticulum aminopeptidase 2 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 960 5q15 ERAP2 endoplasmic reticulum aminopeptidase 2
Previous and Unofficial Names
L-RAP | Leukocyte-derived arginine aminopeptidase
Database Links
Specialist databases
MEROPS M01.024 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number: 3.4.11.-

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 17 [PMID: 23916253] Hs Inhibition 5.1 pIC50 1
pIC50 5.1 (IC50 8.9x10-6 M) [1]


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1. Papakyriakou A, Zervoudi E, Theodorakis EA, Saveanu L, Stratikos E, Vourloumis D. (2013) Novel selective inhibitors of aminopeptidases that generate antigenic peptides. Bioorg. Med. Chem. Lett.23 (17): 4832-6. [PMID:23916253]

How to cite this page

M1: Aminopeptidase N: Endoplasmic reticulum aminopeptidase 2. Last modified on 28/07/2015. Accessed on 20/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1567.