Carboxypeptidase M

Target id: 1596

Nomenclature: Carboxypeptidase M

Family: M14: Carboxypeptidase A

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Carboxypeptidase M has curated GtoImmuPdb data

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 443 12q15 CPM carboxypeptidase M
Mouse - 443 10 D2 Cpm carboxypeptidase M
Rat - 443 7q22 Cpm carboxypeptidase M
Previous and Unofficial Names
renal carboxypeptidase | urinary carboxypeptidase B
Database Links
Specialist databases
MEROPS M14.006 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 3 [PMID: 14640538] Hs Inhibition 7.9 pIC50 1
pIC50 7.9 (IC50 1.3x10-8 M) [1]
Immunopharmacology Comments
Possible role in immune system discussed in [2].


Show »

1. Barrow JC, Nantermet PG, Stauffer SR, Ngo PL, Steinbeiser MA, Mao SS, Carroll SS, Bailey C, Colussi D, Bosserman M et al.. (2003) Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J. Med. Chem.46 (25): 5294-7. [PMID:14640538]

2. Deiteren K, Hendriks D, ScharpĂ© S, Lambeir AM. (2009) Carboxypeptidase M: Multiple alliances and unknown partners. Clin. Chim. Acta399 (1-2): 24-39. [PMID:18957287]

How to cite this page

M14: Carboxypeptidase A: Carboxypeptidase M. Last modified on 25/07/2016. Accessed on 19/02/2018. IUPHAR/BPS Guide to PHARMACOLOGY,