Target id: 1634

Nomenclature: MMP10

Family: M10: Matrix metallopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for MMP10 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 476 11q22.3 MMP10 matrix metallopeptidase 10
Mouse - 476 9 A1 Mmp10 matrix metallopeptidase 10
Rat - 476 8q11 Mmp10 matrix metallopeptidase 10
Previous and Unofficial Names
transin-2 | SL-2 | transformation-associated protein 34A | STMY2 | matrix metallopeptidase 10 (stromelysin 2)
Database Links
Specialist databases
MEROPS M10.006 (Hs)
Other databases
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
CM-352 Hs Inhibition 7.8 pIC50 1
pIC50 7.8 (IC50 1.5x10-8 M) [1]


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1. Orbe J, Rodríguez JA, Sánchez-Arias JA, Salicio A, Belzunce M, Ugarte A, Chang HC, Rabal O, Oyarzabal J, Páramo JA. (2015) Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage. J. Med. Chem., 58 (7): 2941-57. [PMID:25686022]

How to cite this page

M10: Matrix metallopeptidase: MMP10. Last modified on 29/08/2017. Accessed on 22/07/2018. IUPHAR/BPS Guide to PHARMACOLOGY,