Interleukin 3 receptor, α subunit

Target id: 1705

Nomenclature: Interleukin 3 receptor, α subunit

Family: IL-3 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Interleukin 3 receptor, α subunit has curated GtoImmuPdb data

Quaternary Structure: Complexes
Interleukin-3 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 378 Xp22.3 and Yp13.3 IL3RA interleukin 3 receptor subunit alpha
Mouse 1 396 Il3ra interleukin 3 receptor
Rat - - Il3ra interleukin 3 receptor subunit alpha
Previous and Unofficial Names
CD123 | cytokine receptor-like protein CYRL | SUT-1 | interleukin 3 receptor, alpha (low affinity)
Database Links
CATH/Gene3D
DrugBank Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file

Agonists
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Affinity Units Reference
IL-3 {Sp: Human} Hs Agonist - -
Immunopharmacology Comments
This is the ligand binding subunit of the functional IL-3 receptor complex.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process ID:  9
Comment: 
GO Annotation:  Associated to GO processes
GO Processes:  interleukin-3 receptor activity (GO:0004912) TAS
References: 

How to cite this page

IL-3 receptor family: Interleukin 3 receptor, α subunit. Last modified on 22/03/2017. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1705.