acrosin | S1: Chymotrypsin | IUPHAR/BPS Guide to PHARMACOLOGY

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Target not currently curated in GtoImmuPdb

Target id: 2327

Nomenclature: acrosin

Family: S1: Chymotrypsin

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 421 22q13.33 ACR acrosin
Mouse - 436 15 E-F Acr acrosin prepropeptide
Rat - 437 7q34-q35 Acr acrosin
Previous and Unofficial Names
Database Links
Specialist databases
MEROPS S01.223 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Parameter Reference
compound 9 [PMID: 3514912] Hs Inhibition 8.5 pIC50 1
pIC50 8.5 (IC50 3.3x10-9 M) [1]


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1. Kaminski JM, Bauer L, Mack SR, Anderson Jr RA, Waller DP, Zaneveld LJ. (1986) Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates. J. Med. Chem., 29 (4): 514-9. [PMID:3514912]

How to cite this page

S1: Chymotrypsin: acrosin. Last modified on 14/07/2015. Accessed on 19/04/2019. IUPHAR/BPS Guide to PHARMACOLOGY,