chymotrypsin like elastase family member 1 | S1: Chymotrypsin | IUPHAR/BPS Guide to PHARMACOLOGY

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chymotrypsin like elastase family member 1

Target not currently curated in GtoImmuPdb

Target id: 2338

Nomenclature: chymotrypsin like elastase family member 1

Family: S1: Chymotrypsin

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 258 12q13 CELA1 chymotrypsin like elastase family member 1
Mouse - 266 15 F1-F3 Cela1 chymotrypsin-like elastase family
Rat - 266 7q36 Cela1 chymotrypsin-like elastase family
Previous and Unofficial Names
ELA1 | elastase 1, pancreatic | chymotrypsin-like elastase family
Database Links
Specialist databases
MEROPS S01.153 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Parameter Reference
telaprevir Hs Inhibition 7.5 pIC50 1
pIC50 7.5 (IC50 3x10-8 M) [1]


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1. Liverton NJ, Carroll SS, Dimuzio J, Fandozzi C, Graham DJ, Hazuda D, Holloway MK, Ludmerer SW, McCauley JA, McIntyre CJ et al.. (2010) MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. Antimicrob. Agents Chemother., 54 (1): 305-11. [PMID:19841155]

How to cite this page

S1: Chymotrypsin: chymotrypsin like elastase family member 1. Last modified on 29/01/2016. Accessed on 26/03/2019. IUPHAR/BPS Guide to PHARMACOLOGY,