SUMO1/sentrin specific peptidase 1

Target id: 2414

Nomenclature: SUMO1/sentrin specific peptidase 1

Family: C48: Ulp1 endopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for SUMO1/sentrin specific peptidase 1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 644 12q13.1 SENP1 SUMO1/sentrin specific peptidase 1
Mouse - 640 15 54.04 cM Senp1 SUMO1/sentrin specific peptidase 1
Rat - - 7q36 Senp1 SUMO1/sentrin specific peptidase 1
Previous and Unofficial Names
Sentrin-specific protease 1
Database Links
Specialist databases
MEROPS C48.002 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.4.22.68

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 8e [PMID: 23044371] Hs Inhibition 5.7 pIC50 1
pIC50 5.7 (IC50 1.856x10-6 M) [1]

References

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1. Chen Y, Wen D, Huang Z, Huang M, Luo Y, Liu B, Lu H, Wu Y, Peng Y, Zhang J. (2012) 2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation. Bioorg. Med. Chem. Lett.22 (22): 6867-70. [PMID:23044371]

How to cite this page

C48: Ulp1 endopeptidase: SUMO1/sentrin specific peptidase 1. Last modified on 16/09/2015. Accessed on 21/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2414.