SUMO specific peptidase 1

Target id: 2414

Nomenclature: SUMO specific peptidase 1

Family: C48: Ulp1 endopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for SUMO specific peptidase 1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 644 12q13.1 SENP1 SUMO specific peptidase 1
Mouse - 640 15 54.04 cM Senp1 SUMO1/sentrin specific peptidase 1
Rat - - 7q36 Senp1 SUMO1/sentrin specific peptidase 1
Previous and Unofficial Names
Sentrin-specific protease 1 | SUMO1/sentrin specific peptidase 1
Database Links
Specialist databases
MEROPS C48.002 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
compound 8e [PMID: 23044371] Hs Inhibition 5.7 pIC50 1
pIC50 5.7 (IC50 1.856x10-6 M) [1]


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1. Chen Y, Wen D, Huang Z, Huang M, Luo Y, Liu B, Lu H, Wu Y, Peng Y, Zhang J. (2012) 2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation. Bioorg. Med. Chem. Lett.22 (22): 6867-70. [PMID:23044371]

How to cite this page

C48: Ulp1 endopeptidase: SUMO specific peptidase 1. Last modified on 27/02/2018. Accessed on 24/03/2018. IUPHAR/BPS Guide to PHARMACOLOGY,