bromodomain adjacent to zinc finger domain 1B

Target id: 2774

Nomenclature: bromodomain adjacent to zinc finger domain 1B

Family: Non-enzymatic BRD containing proteins

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for bromodomain adjacent to zinc finger domain 1B in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1483 7q11.23 BAZ1B bromodomain adjacent to zinc finger domain 1B
Mouse - 1479 5 G2 Baz1b bromodomain adjacent to zinc finger domain, 1B
Rat - 1476 12q12 Baz1b bromodomain adjacent to zinc finger domain, 1B
Previous and Unofficial Names
WBSCR10 | WBSCR9 | Williams-Beuren syndrome chromosome region 10 | WSTF | bromodomain adjacent to zinc finger domain, 1B | bromodomain adjacent to zinc finger domain
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Physiological Consequences of Altering Gene Expression
BAZ1B (WSTF)-deficient mice exhibit some of the heart defects and abnormal calcium metabolism observed in Williams syndrome
Species:  Mouse
Tissue:  In vivo, cardiac tissue
Technique:  Gene knockout
References:  1
Gene Expression and Pathophysiology
Deletion of BAZ1B has been identified in patients with Williams-Beuren syndrome (WBS)
Tissue or cell type: 
Pathophysiology:  Williams-Beuren syndrome (WBS)
Species:  Human
Technique:  Fluorescence in situ hybridization and gene doasge analysis
References:  2-3

References

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1. Kitagawa H, Fujiki R, Yoshimura K, Oya H, Kato S. (2011) Williams syndrome is an epigenome-regulator disease. Endocr. J.58 (2): 77-85. [PMID:21242649]

2. Lu X, Meng X, Morris CA, Keating MT. (1998) A novel human gene, WSTF, is deleted in Williams syndrome. Genomics54 (2): 241-9. [PMID:9828126]

3. Peoples RJ, Cisco MJ, Kaplan P, Francke U. (1998) Identification of the WBSCR9 gene, encoding a novel transcriptional regulator, in the Williams-Beuren syndrome deletion at 7q11.23. Cytogenet. Cell Genet.82 (3-4): 238-46. [PMID:9858827]

How to cite this page

Non-enzymatic BRD containing proteins: bromodomain adjacent to zinc finger domain 1B. Last modified on 13/02/2017. Accessed on 20/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2774.