farnesyltransferase, CAAX box, alpha

Target id: 2825

Nomenclature: farnesyltransferase, CAAX box, alpha

Abbreviated Name: FNTA

Family: 2.5.1.58 Protein farnesyltransferase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for farnesyltransferase, CAAX box, alpha in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 379 8p11.21 FNTA farnesyltransferase, CAAX box, alpha
Mouse - 377 8 A2 Fnta farnesyltransferase, CAAX box, alpha
Rat - 377 16q12.4 Fnta farnesyltransferase, CAAX box, alpha
Previous and Unofficial Names
farnesyltransferase
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 2.5.1.58
Inhibitor Comments
Note that for farnesyltransferase inhibitors we map the ligand interaction to the beta subunit (FNTB), although the actual active site forms in the centre of the beta subunit overlapped by the alpha subunit.

How to cite this page

2.5.1.58 Protein farnesyltransferase: farnesyltransferase, CAAX box, alpha. Last modified on 13/08/2015. Accessed on 24/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2825.