protein phosphatase methylesterase 1

Target id: 2875

Nomenclature: protein phosphatase methylesterase 1

Family: 3.1.1.- Carboxylic Ester Hydrolases, S33: Prolyl aminopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for protein phosphatase methylesterase 1 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 400 11q13.4 PPME1 protein phosphatase methylesterase 1
Mouse - 386 7 F! Ppme1 protein phosphatase methylesterase 1
Rat - 386 1q32 Ppme1 protein phosphatase methylesterase 1
Previous and Unofficial Names
PME-1 | PME1
Database Links
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
ABL127 Hs Inhibition 7.9 pIC50 1
pIC50 7.9 (IC50 1.2x10-8 M) [1]


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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat. Chem. Biol., 10 (8): 656-63. [PMID:24997602]

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: protein phosphatase methylesterase 1. Last modified on 24/08/2015. Accessed on 18/07/2018. IUPHAR/BPS Guide to PHARMACOLOGY,