Aryl hydrocarbon receptor

Target id: 2951

Nomenclature: Aryl hydrocarbon receptor

Family: Aryl hydrocarbon receptor complex

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for Aryl hydrocarbon receptor in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 838 7p21.1 AHR aryl hydrocarbon receptor
Mouse - 839 12 A3 Ahr aryl-hydrocarbon receptor
Rat - 844 6q16 Ahr aryl hydrocarbon receptor
Database Links
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Crystal structure of the AHR-ARNT heterodimer in complex with the DRE
PDB Id:  5V0L
Resolution:  4.0Å
Species:  Human
References:  1
Other Binding Ligands
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Affinity Units Reference
TCDD Hs Binding - -

References

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1. Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. (2017) Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc. Natl. Acad. Sci. U.S.A.114 (21): 5431-5436. [PMID:28396409]

How to cite this page

Aryl hydrocarbon receptor complex: Aryl hydrocarbon receptor. Last modified on 17/08/2017. Accessed on 23/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2951.