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E2 ubiquitin-conjugating enzymes

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

3228
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ubiquitin conjugating enzyme E2 D1 Show summary »

Target Id 3228
Nomenclature ubiquitin conjugating enzyme E2 D1
Genes UBE2D1 (Hs), Ube2d1 (Mm), Ube2d1 (Rn)
Ensembl ID ENSG00000072401 (Hs), ENSMUSG00000019927 (Mm), ENSRNOG00000000611 (Rn)
UniProtKB AC P51668 (Hs), P61080 (Mm), D3ZDK2 (Rn)
EC number
2.3.2.23
2.3.2.24
Ligands
EN450 (Binding) (degrader) [1]
Comment One of four human UBE2D genes (UBE2D1-4), that encode E2 ubiquitin-conjugating enzymes, that are involved in the second step in the ubiquitination process that ultimately leads to proteosome-mediated protein degradation.

ubiquitin conjugating enzyme E2 D2 Show summary »

References

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How to cite this family page

Database page citation:

E2 ubiquitin-conjugating enzymes. Accessed on 26/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1078.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.