ENaC β

Target id: 739

Nomenclature: ENaC β

Family: Epithelial sodium channels (ENaC)

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Quaternary Structure: Complexes
ENaCαβγ
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 640 16p12.2-p12.1 SCNN1B sodium channel, non voltage gated 1 beta subunit
Mouse - 638 7 F2 Scnn1b sodium channel, nonvoltage-gated 1 beta
Rat - 638 1q36-q41 Scnn1b sodium channel, non-voltage-gated 1, beta subunit
Previous and Unofficial Names
ENaCbeta
beta-ENaC
beta-NaCH
epithelial Na(+) channel subunit beta
RNENACB
SCNEB
ENaC beta
sodium channel, non-voltage-gated 1, beta subunit
Database Links
DrugBank Target
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
Human Protein Reference Database
InterPro
KEGG Gene
NeXtProt
OMIM
PhosphoSitePlus
TreeFam
UniProtKB
Wikipedia
Natural/Endogenous Ligands
sodium
Clinically-Relevant Mutations and Pathophysiology
Disease:  Bronchiectasis with or without elevated sweat chloride 1, BESC1
Synonyms: Bronchiectasis [Disease Ontology: DOID:9563]
Idiopathic bronchiectasis [Orphanet: ORPHA60033]
Disease Ontology: DOID:9563
OMIM: 211400
Orphanet: ORPHA60033
Disease:  Liddle syndrome; LIDLS
Disease Ontology: DOID:0050477
OMIM: 177200
Orphanet: ORPHA526
Disease:  Pseudohypoaldosteronism, type I, autosomal recessive; PHA1B
Synonyms: Autosomal recessive pseudohypoaldosteronism type 1 [Orphanet: ORPHA171876]
Generalized pseudohypoaldosteronism type 1 [Orphanet: ORPHA171876]
Pseudohypoaldosteronism [Disease Ontology: DOID:4479]
Disease Ontology: DOID:4479
OMIM: 264350
Orphanet: ORPHA171876

How to cite this page

Epithelial sodium channels (ENaC): ENaC β. Last modified on 05/08/2015. Accessed on 31/08/2015. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=739.