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P1B P-type ATPases: Cu+-ATPases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Copper-transporting ATPases convey copper ions across cell-surface and intracellular membranes. They consist of eight TM domains and associate with multiple copper chaperone proteins (e.g. ATOX1, O00244).

Transporters

852
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ATP7A Show summary »

Target Id 852
Nomenclature ATP7A
Previous and unofficial names copper pump 1 | Copper-transporting ATPase 1 | Menkes disease-associated protein | ATPase Cu++ transporting alpha polypeptide (Menkes syndrome) | ATPase, Cu� transporting, alpha polypeptide | ATPase
Genes ATP7A (Hs), Atp7a (Mm), Atp7a (Rn)
Ensembl ID ENSG00000165240 (Hs), ENSMUSG00000033792 (Mm), ENSRNOG00000061367 (Rn)
UniProtKB AC Q04656 (Hs), Q64430 (Mm), P70705 (Rn)
EC number
3.6.3.4

ATP7B Show summary »

NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.