P4 P-type ATPases: Phospholipid-transporting ATPases | Transporters

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P4 P-type ATPases: Phospholipid-transporting ATPases

P4 P-type ATPases: Phospholipid-transporting ATPases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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These transporters are thought to translocate the aminophospholipids phosphatidylserine and phosphatidylethanolamine from one side of the phospholipid bilayer to the other to generate asymmetric membranes. They are also proposed to be involved in the generation of vesicles from intracellular and cell-surface membranes.

Transporters

865

ATP8A1 (Phospholipid-transporting ATPase IA) Show summary »« Hide summary

Target Id

854

Nomenclature

Phospholipid-transporting ATPase IA

Common abbreviation

ATP8A1

Previous and unofficial names

Genes

ATP8A1 (Hs), Atp8a1 (Mm), Atp8a1 (Rn)

Ensembl ID

ENSG00000124406 (Hs), ENSMUSG00000037685 (Mm), ENSRNOG00000034200 (Rn)

UniProtKB AC

Q9Y2Q0 (Hs), P70704 (Mm)

EC number

3.6.3.1

ATP8A2 (Phospholipid-transporting ATPase IB) Show summary »« Hide summary

Target Id

855

Nomenclature

Phospholipid-transporting ATPase IB

Common abbreviation

ATP8A2

Previous and unofficial names

Genes

ATP8A2 (Hs), Atp8a2 (Mm)

Ensembl ID

ENSG00000132932 (Hs), ENSMUSG00000021983 (Mm)

UniProtKB AC

Q9NTI2 (Hs), P98200 (Mm)

EC number

3.6.3.1

ATP8B1 (Phospholipid-transporting ATPase IC) Show summary »« Hide summary

Target Id

856

Nomenclature

Phospholipid-transporting ATPase IC

Common abbreviation

ATP8B1

Previous and unofficial names

Genes

ATP8B1 (Hs), Atp8b1 (Mm), Atp8b1 (Rn)

Ensembl ID

ENSG00000081923 (Hs), ENSMUSG00000039529 (Mm), ENSRNOG00000024952 (Rn)

UniProtKB AC

O43520 (Hs), Q148W0 (Mm)

EC number

3.6.3.1

ATP8B2 (Phospholipid-transporting ATPase ID) Show summary »« Hide summary

Target Id

857

Nomenclature

Phospholipid-transporting ATPase ID

Common abbreviation

ATP8B2

Previous and unofficial names

ATPID | ATPase, class I, type 8B, member 2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | ATPase

Genes

ATP8B2 (Hs), Atp8b2 (Mm), Atp8b2 (Rn)

Ensembl ID

ENSG00000143515 (Hs), ENSMUSG00000060671 (Mm), ENSRNOG00000020822 (Rn)

UniProtKB AC

P98198 (Hs), P98199 (Mm)

EC number

3.6.3.1

ATP8B3 (Phospholipid-transporting ATPase IK) Show summary »« Hide summary

Target Id

858

Nomenclature

Phospholipid-transporting ATPase IK

Common abbreviation

ATP8B3

Previous and unofficial names

Genes

ATP8B3 (Hs), Atp8b3 (Mm), Atp8b3 (Rn)

Ensembl ID

ENSG00000130270 (Hs), ENSMUSG00000003341 (Mm), ENSRNOG00000024975 (Rn)

UniProtKB AC

O60423 (Hs)

EC number

3.6.3.1

ATP8B4 (Probable phospholipid-transporting ATPase IM) Show summary »« Hide summary

Target Id

859

Nomenclature

Probable phospholipid-transporting ATPase IM

Common abbreviation

ATP8B4

Previous and unofficial names

ATPIM | ATPase, Class I, type 8B, member 4 | ATPase, class I, type 8B, member 4 | ATPase

Genes

ATP8B4 (Hs), Atp8b4 (Mm), Atp8b4 (Rn)

Ensembl ID

ENSG00000104043 (Hs), ENSMUSG00000060131 (Mm), ENSRNOG00000031598 (Rn)

UniProtKB AC

Q8TF62 (Hs)

EC number

3.6.3.1

ATP9A (Probable phospholipid-transporting ATPase IIA) Show summary »« Hide summary

Target Id

860

Nomenclature

Probable phospholipid-transporting ATPase IIA

Common abbreviation

ATP9A

Previous and unofficial names

ATPase IIA | ATPIIA | ATPase, Class II, type 9A | ATPase, class II, type 9A | ATPase

Genes

ATP9A (Hs), Atp9a (Mm), Atp9a (Rn)

Ensembl ID

ENSG00000054793 (Hs), ENSMUSG00000027546 (Mm), ENSRNOG00000049484 (Rn)

UniProtKB AC

O75110 (Hs), O70228 (Mm)

EC number

3.6.3.1

ATP9B (Probable phospholipid-transporting ATPase IIB) Show summary »« Hide summary

Target Id

861

Nomenclature

Probable phospholipid-transporting ATPase IIB

Common abbreviation

ATP9B

Previous and unofficial names

ATPase class II type 9B | ATPIIB | ATPase, class II, type 9B | ATPase

Genes

ATP9B (Hs), Atp9b (Mm), Atp9b (Rn)

Ensembl ID

ENSG00000166377 (Hs), ENSMUSG00000024566 (Mm), ENSRNOG00000032039 (Rn)

UniProtKB AC

O43861 (Hs), P98195 (Mm), D4ABB8 (Rn)

EC number

3.6.3.1

ATP10A (Probable phospholipid-transporting ATPase VA) Show summary »« Hide summary

Target Id

862

Nomenclature

Probable phospholipid-transporting ATPase VA

Common abbreviation

ATP10A

Previous and unofficial names

Genes

ATP10A (Hs), Atp10a (Mm), Atp10a (Rn)

Ensembl ID

ENSG00000206190 (Hs), ENSMUSG00000025324 (Mm), ENSRNOG00000056228 (Rn)

UniProtKB AC

O60312 (Hs), O54827 (Mm)

EC number

3.6.3.1

ATP10B (Probable phospholipid-transporting ATPase VB) Show summary »« Hide summary

Target Id

863

Nomenclature

Probable phospholipid-transporting ATPase VB

Common abbreviation

ATP10B

Previous and unofficial names

ATPase class V type 10B | ATPVB | ATPase, class V, type 10B | ATPase | ATPase phospholipid transporting 10B (putative)

Genes

ATP10B (Hs), Atp10b (Mm), Atp10b (Rn)

Ensembl ID

ENSG00000118322 (Hs), ENSMUSG00000055415 (Mm), ENSRNOG00000003781 (Rn)

UniProtKB AC

O94823 (Hs)

EC number

3.6.3.1

ATP10D (Probable phospholipid-transporting ATPase VD) Show summary »« Hide summary

Target Id

864

Nomenclature

Probable phospholipid-transporting ATPase VD

Common abbreviation

ATP10D

Previous and unofficial names

ATPase class V type 10D | ATPVD | ATPase, class V, type 10D | ATPase

Genes

ATP10D (Hs), Atp10d (Mm), Atp10d (Rn)

Ensembl ID

ENSG00000145246 (Hs), ENSMUSG00000046808 (Mm), ENSRNOG00000002312 (Rn)

UniProtKB AC

Q9P241 (Hs), Q8K2X1 (Mm)

EC number

3.6.3.1

ATP11A (Probable phospholipid-transporting ATPase IH) Show summary »« Hide summary

Target Id

865

Nomenclature

Probable phospholipid-transporting ATPase IH

Common abbreviation

ATP11A

Previous and unofficial names

Genes

ATP11A (Hs), Atp11a (Mm), Atp11a (Rn)

Ensembl ID

ENSG00000068650 (Hs), ENSMUSG00000031441 (Mm), ENSRNOG00000017154 (Rn)

UniProtKB AC

P98196 (Hs), P98197 (Mm)

EC number

3.6.3.1

ATP11B (Probable phospholipid-transporting ATPase IF) Show summary »« Hide summary

Target Id

866

Nomenclature

Probable phospholipid-transporting ATPase IF

Common abbreviation

ATP11B

Previous and unofficial names

Genes

ATP11B (Hs), Atp11b (Mm), Atp11b (Rn)

Ensembl ID

ENSG00000058063 (Hs), ENSMUSG00000037400 (Mm), ENSRNOG00000052116 (Rn)

UniProtKB AC

Q9Y2G3 (Hs)

EC number

3.6.3.1

ATP11C (Phospholipid-transporting ATPase IG) Show summary »« Hide summary

Target Id

867

Nomenclature

Phospholipid-transporting ATPase IG

Common abbreviation

ATP11C

Previous and unofficial names

Genes

ATP11C (Hs), Atp11c (Mm), Atp11c (Rn)

Ensembl ID

ENSG00000101974 (Hs), ENSMUSG00000062949 (Mm), ENSRNOG00000003472 (Rn)

UniProtKB AC

Q8NB49 (Hs), Q9QZW0 (Mm)

EC number

3.6.3.1

transmembrane protein 30A Show summary »« Hide summary

Comments

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References

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How to cite this family page

Database page citation:

P4 P-type ATPases: Phospholipid-transporting ATPases. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=162.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.