Toggle GtoImmuPdb View Expand all nodesCollapse all nodes

* Key recommended reading is highlighted with an asterisk

Andres-Barquin PJ, Conte C. (2004) Molecular basis of bitter taste: the T2R family of G protein-coupled receptors. Cell Biochem. Biophys., 41 (1): 99-112. [PMID:15371642]

Bachmanov AA, Beauchamp GK. (2007) Taste receptor genes. Annu. Rev. Nutr., 27: 389-414. [PMID:17444812]

Blaho VA, Hla T. (2011) Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors. Chem. Rev., 111 (10): 6299-320. [PMID:21939239]

Chi H. (2011) Sphingosine-1-phosphate and immune regulation: trafficking and beyond. Trends Pharmacol. Sci., 32 (1): 16-24. [PMID:21159389]

Chun J, Hla T, Lynch KR, Spiegel S, Moolenaar WH. (2010) International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature. Pharmacol. Rev., 62 (4): 579-87. [PMID:21079037]

* Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR et al.. (2013) International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol. Rev., 65 (3): 967-86. [PMID:23686350]

de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. (2000) International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol. Rev., 52: 415-472. [PMID:10977869]

DeSimone JA, Lyall V. (2006) Taste receptors in the gastrointestinal tract III. Salty and sour taste: sensing of sodium and protons by the tongue. Am. J. Physiol. Gastrointest. Liver Physiol., 291 (6): G1005-10. [PMID:16809639]

Ellis B, Li XC, Miguel-Qin E, Gu V, Zhuo JL. (2012) Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol., 302 (5): R494-509. [PMID:22170616]

Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin JP, Davenport AP, Spedding M, Harmar AJ. (2005) International Union of Pharmacology. XLVI. G protein-coupled receptor list. Pharmacol Rev, 57: 279-288. [PMID:15914470]

Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB. (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol, 63: 1256-1272. [PMID:12761335]

* Gilissen J, Jouret F, Pirotte B, Hanson J. (2016) Insight into SUCNR1 (GPR91) structure and function. Pharmacol. Ther., 159: 56-65. [PMID:26808164]

* Insel PA, Wilderman A, Zambon AC, Snead AN, Murray F, Aroonsakool N, McDonald DS, Zhou S, McCann T, Zhang L et al.. (2015) G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets. Mol. Pharmacol., 88 (1): 181-7. [PMID:25737495]

* Khan MZ, He L. (2017) Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors. Psychopharmacology (Berl.), 234 (8): 1181-1207. [PMID:28289782]

Kinnamon SC. (2012) Taste receptor signalling - from tongues to lungs. Acta Physiol (Oxf), 204 (2): 158-68. [PMID:21481196]

Lagerström MC, Schiöth HB. (2008) Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov, 7 (4): 339-57. [PMID:18382464]

Maceyka M, Harikumar KB, Milstien S, Spiegel S. (2012) Sphingosine-1-phosphate signaling and its role in disease. Trends Cell Biol., 22 (1): 50-60. [PMID:22001186]

MacKenzie A. (2011) Endothelium-derived vasoactive agents, AT1 receptors and inflammation. Pharmacol. Ther., 131 (2): 187-203. [PMID:21115037]

* Mackenzie AE, Milligan G. (2017) The emerging pharmacology and function of GPR35 in the nervous system. Neuropharmacology, 113 (Pt B): 661-671. [PMID:26232640]

Meyerhof W. (2005) Elucidation of mammalian bitter taste. Rev. Physiol. Biochem. Pharmacol., 154: 37-72. [PMID:16032395]

Mutoh T, Rivera R, Chun J. (2012) Insights into the pharmacological relevance of lysophospholipid receptors. Br. J. Pharmacol., 165 (4): 829-44. [PMID:21838759]

* Ngo T, Kufareva I, Coleman JLj, Graham RM, Abagyan R, Smith NJ. (2016) Identifying ligands at orphan GPCRs: current status using structure-based approaches. Br. J. Pharmacol., 173 (20): 2934-51. [PMID:26837045]

O'Sullivan C, Dev KK. (2013) The structure and function of the S1P1 receptor. Trends Pharmacol. Sci., 34 (7): 401-12. [PMID:23763867]

Overington JP, Al-Lazikani B, Hopkins AL. (2006) How many drug targets are there?. Nat Rev Drug Discov, 5 (12): 993-6. [PMID:17139284]

Patel BM, Mehta AA. (2012) Aldosterone and angiotensin: Role in diabetes and cardiovascular diseases. Eur. J. Pharmacol., 697 (1-3): 1-12. [PMID:23041273]

Putnam K, Shoemaker R, Yiannikouris F, Cassis LA. (2012) The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome. Am. J. Physiol. Heart Circ. Physiol., 302 (6): H1219-30. [PMID:22227126]

Pyne S, Pyne NJ. (2011) Translational aspects of sphingosine 1-phosphate biology. Trends Mol Med, 17 (8): 463-72. [PMID:21514226]

Renwick AG, Molinary SV. (2010) Sweet-taste receptors, low-energy sweeteners, glucose absorption and insulin release. Br. J. Nutr., 104 (10): 1415-20. [PMID:20619074]

Ross RA. (2009) The enigmatic pharmacology of GPR55. Trends Pharmacol. Sci., 30 (3): 156-63. [PMID:19233486]

Rozengurt E. (2006) Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and alpha-gustducin in the mammalian gut. Am. J. Physiol. Gastrointest. Liver Physiol., 291 (2): G171-7. [PMID:16710053]

Rozengurt E, Sternini C. (2007) Taste receptor signaling in the mammalian gut. Curr Opin Pharmacol, 7 (6): 557-62. [PMID:18024184]

Sevá Pessôa B, van der Lubbe N, Verdonk K, Roks AJ, Hoorn EJ, Danser AH. (2013) Key developments in renin-angiotensin-aldosterone system inhibition. Nat Rev Nephrol, 9 (1): 26-36. [PMID:23165302]

Spiegel S, Milstien S. (2011) The outs and the ins of sphingosine-1-phosphate in immunity. Nat. Rev. Immunol., 11 (6): 403-15. [PMID:21546914]

Temussi PA. (2009) Sweet, bitter and umami receptors: a complex relationship. Trends Biochem. Sci., 34 (6): 296-302. [PMID:19443222]

Tepper BJ. (2008) Nutritional implications of genetic taste variation: the role of PROP sensitivity and other taste phenotypes. Annu. Rev. Nutr., 28: 367-88. [PMID:18407743]

Yarmolinsky DA, Zuker CS, Ryba NJ. (2009) Common sense about taste: from mammals to insects. Cell, 139 (2): 234-44. [PMID:19837029]

Yona S, Lin HH, Siu WO, Gordon S, Stacey M. (2008) Adhesion-GPCRs: emerging roles for novel receptors. Trends Biochem. Sci., 33 (10): 491-500. [PMID:18789697]