SLC37 family of phosphosugar/phosphate exchangers

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The family of sugar-phosphate exchangers pass particular phosphorylated sugars across intracellular membranes, exchanging for inorganic phosphate. Of the family of sugar phosphate transporters, most information is available on SPX4, the glucose-6-phosphate transporter. This is a 10 TM domain protein with cytoplasmic termini and is associated with the endoplasmic reticulum, with tissue-specific splice variation.

Transporters

SPX1 (Glycerol-3-phosphate transporter / SLC37A1) Show summary »

SPX2 / SLC37A2 Show summary »

SPX3 / SLC37A3 Show summary »

SPX4 (Glucose-6-phosphate transporter / SLC37A4) Show summary »

Further reading

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References

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How to cite this family page

Database page citation:

SLC37 family of phosphosugar/phosphate exchangers. Accessed on 23/07/2014. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=224.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA and Harmar AJ, CGTP Collaborators. (2013) The Concise Guide to PHARMACOLOGY 2013/14: Transporters. Br J Pharmacol. 170: 1706–1796.