P2Y receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

« Hide More detailed introduction

P2Y receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on P2Y Receptors [1-2]) are activated by the endogenous ligands ATP, adenosine diphosphate, uridine triphosphate, uridine diphosphate and UDP-glucose. The relationship of many of the cloned receptors to endogenously expressed receptors is not yet established and so it might be appropriate to use wording such as ‘uridine triphosphate-preferring (or ATP-, etc.) P2Y receptor’ or ‘P2Y1-like’, etc., until further, as yet undefined, corroborative criteria can be applied [13,24,36,65,69].

Receptors

P2Y1 receptor Show summary » More detailed page

P2Y2 receptor Show summary » More detailed page

P2Y4 receptor Show summary » More detailed page

P2Y6 receptor Show summary » More detailed page

P2Y11 receptor Show summary » More detailed page

P2Y12 receptor Show summary » More detailed page

P2Y13 receptor Show summary » More detailed page

P2Y14 receptor Show summary » More detailed page

Comments

Show »

Further reading

Show »

References

Show »

NC-IUPHAR subcommittee and family contributors

Show »

How to cite this family page

Database page citation:

Geoffrey Burnstock, Maria-Pia Abbracchio, Jean-Marie Boeynaems, José L. Boyer, Stefania Ceruti, Marta Fumagalli, Christian Gachet, Robert G. Humphries, Kenneth A. Jacobson, Charles Kennedy, Brian F. King, Davide Lecca, Maria Teresa Miras-Portugal, Gary A. Weisman, Rebecca Hills. P2Y receptors. Accessed on 28/08/2016. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=52.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol. 172: 5744-5869.