1B. Retinoic acid receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Retinoic acid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [5]) are nuclear hormone receptors of the NR1B family activated by the vitamin A-derived agonists tretinoin (ATRA) and alitretinoin, and the RAR-selective synthetic agonists TTNPB and adapalene. BMS493 is a family-selective antagonist [6].

Receptors

Retinoic acid receptor-α / NR1B1 Show summary » More detailed page

Retinoic acid receptor-β / NR1B2 Show summary » More detailed page

Retinoic acid receptor-γ / NR1B3 Show summary » More detailed page

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How to cite this family page

Database page citation:

1B. Retinoic acid receptors. Accessed on 05/05/2016. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=85.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Cidlowski JA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors. Br J Pharmacol. 172: 5956-5978.