EWB-3-14 [Ligand Id: 12730] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL397276 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
| ChEMBL | Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells | B | 7.05 | pKi | 90 | nM | Ki | J Med Chem (2007) 50: 3765-3776 [PMID:17625813] |
| κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] | ||||||||
| ChEMBL | Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells | B | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2007) 50: 3765-3776 [PMID:17625813] |
| μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] | ||||||||
| GtoPdb | Displacement of [125I]Ioxycodone from human mu opioid receptor expressed in CHO cells | - | 9.22 | pKi | 0.6 | nM | Ki | J Med Chem (2007) 50: 3765-76 [PMID:17625813] |
| ChEMBL | Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells | B | 9.22 | pKi | 0.6 | nM | Ki | J Med Chem (2007) 50: 3765-3776 [PMID:17625813] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
