IACS-52825 [Ligand Id: 12909] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| mitogen-activated protein kinase kinase kinase 12 in Human [GtoPdb: 2072] [UniProtKB: Q12852] | ||||||||
| GtoPdb | Binding dissociation constant determined in the proprietary KINOMEscan KdELECT system | - | 8.89 | pKd | 1.3 | nM | Kd | J Med Chem (2023) 66: 9954-9971 [PMID:37436942] |
| GtoPdb | Inhibition of c-Jun phosphorylation in HEK293 cells stably expressing hDLK | - | 6.97 | pIC50 | 107 | nM | IC50 | J Med Chem (2023) 66: 9954-9971 [PMID:37436942] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
