compound 111 [PMID: 37918435] [Ligand Id: 12997] activity data from GtoPdb

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  • Nerve Growth factor IB in Human [GtoPdb: 629] [UniProtKB: P22736]
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  • Nuclear receptor related 1 in Human [GtoPdb: 630] [UniProtKB: P43354]
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  • Neuron-derived orphan receptor 1 in Human [GtoPdb: 631] [UniProtKB: Q92570]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Nerve Growth factor IB in Human [GtoPdb: 629] [UniProtKB: P22736]
GtoPdb - - 7.4 pEC50 40 nM EC50 J Med Chem (2023) 66: 15362-15369 [PMID:37918435]
Nuclear receptor related 1 in Human [GtoPdb: 630] [UniProtKB: P43354]
GtoPdb - - 6.77 pKd 170 nM Kd J Med Chem (2023) 66: 15362-15369 [PMID:37918435]
GtoPdb - - 7.05 pEC50 90 nM EC50 J Med Chem (2023) 66: 15362-15369 [PMID:37918435]
Neuron-derived orphan receptor 1 in Human [GtoPdb: 631] [UniProtKB: Q92570]
GtoPdb - - 6.82 pEC50 150 nM EC50 J Med Chem (2023) 66: 15362-15369 [PMID:37918435]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.