LP99 [Ligand Id: 8572] activity data from GtoPdb

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  • bromodomain containing 7 in Human [GtoPdb: 2726] [UniProtKB: Q9NPI1]
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  • bromodomain containing 9 in Human [GtoPdb: 2728] [UniProtKB: Q9H8M2]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
bromodomain containing 7 in Human [GtoPdb: 2726] [UniProtKB: Q9NPI1]
GtoPdb Based on binding of BRD7 being 10-fold lower than for BRD9 - 6 pKd ~1000 nM Kd Angew Chem Int Ed Engl (2015) 54: 6217-21 [PMID:25864491]
bromodomain containing 9 in Human [GtoPdb: 2728] [UniProtKB: Q9H8M2]
GtoPdb Isothermal titration calorimetry (ITC) assay - 7 pKd 99 nM Kd Angew Chem Int Ed Engl (2015) 54: 6217-21 [PMID:25864491]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.