fulvestrant

Ligand Id: 1015
Ligand name fulvestrant

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 15
Topological polar surface area 76.74
Molecular weight 606.32
XLogP 10.61
No. Lipinski's rules broken 2

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2002))
IUPAC Name
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
International Nonproprietary Names
INN number INN
7712 fulvestrant
Synonyms
Faslodex®
ICI 182,780
ICI 182780
ICI182780
ZD-9238
Database Links
BindingDB Ligand 50169743
CAS Registry No. 129453-61-8
ChEMBL Ligand CHEMBL1358
DrugBank Ligand DB00947
NURSA Ligand li9
PharmGKB Drug PA10086, PA164747170
PubChem CID 104741
Search Google for chemical match using the InChIKey VWUXBMIQPBEWFH-WCCTWKNTSA-N
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Wikipedia Fulvestrant
Comments
Fulvestrant is an estrogen receptor antagonist.