hCG   Click here for help

GtoPdb Ligand ID: 1160

Synonyms: CG | human chorionic gonadotropin
Compound class: Endogenous peptide in human, mouse or rat
Comment: hCG is a heterodimeric protein, consisting of an α subunit (CGA; that it shares with LH, FSH and TSH) and a unique β subunit (CGB3).
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: hcg

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
CG | human chorionic gonadotropin
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CGA glycoprotein hormones, alpha polypeptide Human glycoprotein hormones alpha chain chorionic gonadotropin, alpha polypeptide, follicle-stimulating hormone alpha subunit, FSHA, glycoprotein hormones alpha chain, GPHa, GPHA1, HCG, LHA, luteinizing hormone alpha chain, lutropin alpha chain, thyroid-stimulating hormone alpha chain, TSHA
CGB3 chorionic gonadotropin subunit beta 3 Human chorionic gonadotropin, beta polypeptide precursor CGB, CGB3, chorionic gonadotropin, beta polypeptide, chorionic gonadotropin beta subunit 3
Database Links Click here for help
Specialist databases
GPCRdb Ligand hCG
Other databases
Ensembl Gene ENSG00000135346 (Hs), ENSG00000104827 (Hs)
GtoPdb PubChem SID 135651787
Human Protein Atlas ENSG00000135346 (Hs), ENSG00000104827 (Hs)
Wikipedia Human_chorionic_gonadotropin