|
Synonyms: CG | human chorionic gonadotropin
Compound class:
Endogenous peptide in human, mouse or rat
Comment: hCG is a heterodimeric protein, consisting of an α subunit (CGA; that it shares with LH, FSH and TSH) and a unique β subunit (CGB3).
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖
View more information in the IUPHAR Pharmacology Education Project: hcg |
| References |
|
1. Jia XC, Oikawa M, Bo M, Tanaka T, Ny T, Boime I, Hsueh AJ. (1991)
Expression of human luteinizing hormone (LH) receptor: interaction with LH and chorionic gonadotropin from human but not equine, rat, and ovine species. Mol Endocrinol, 5: 759-768. [PMID:1922095] |
|
2. Müller T, Gromoll J, Simoni M. (2003)
Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action. J Clin Endocrinol Metab, 88 (5): 2242-9. [PMID:12727981] |
