Compound class:
Synthetic organic
Comment: KC-180-2 is a dual action tubulin polymerisation inhibitor and Src kinase inhibitor that was developed as a refined derivative of the anti-cancer agent tirbanibulin (KX2-391) [1]. Destabilisation of tubulin polymers is the primary mechanism that underlies KC-180-2's effects on cell cycle arrest in cancer cells. KC-180-2 occupies the same non-ATP substrate binding pocket within Src as KX2-391.
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Classification | |
Compound class | Synthetic organic |
Database Links | |
GtoPdb PubChem SID | 472319298 |
PubChem CID | 165368934 |
Search Google for chemical match using the InChIKey | KUPDBUBFYCYCNJ-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | KUPDBUBFYCYCNJ |
UniChem Compound Search for chemical match using the InChIKey | KUPDBUBFYCYCNJ-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | KUPDBUBFYCYCNJ-UHFFFAOYSA-N |