latanoprost (free acid form)

Ligand id: 1960

Name: latanoprost (free acid form)

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 12
Topological polar surface area 97.99
Molecular weight 390.24
XLogP 5.23
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1996))
Prodrug latanoprost (isopropyl ester)
IUPAC Name
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid
Synonyms
latanoprost-free acid | PHXA85
Database Links
ChEBI CHEBI:63925
ChEMBL Ligand CHEMBL1050
GtoPdb PubChem SID 135650508
PubChem CID 6441636
Search Google for chemical match using the InChIKey HNPFPERDNWXAGS-NFVOFSAMSA-N
Search Google for chemicals with the same backbone HNPFPERDNWXAGS
Search UniChem for chemical match using the InChIKey HNPFPERDNWXAGS-NFVOFSAMSA-N
Search UniChem for chemicals with the same backbone HNPFPERDNWXAGS
Comments
The active free acid form of latanoprost results from metabolism of the prodrug latanoprost (isopropyl ester).