gentamicin

Ligand id: 2427

Name: gentamicin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 8
Rotatable bonds 7
Topological polar surface area 199.73
Molecular weight 477.32
XLogP -2.88
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1970))
IUPAC Name
2-[4,6-diamino-3-[3-amino-6-(1-methylaminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol
International Nonproprietary Names
INN number INN
1617 gentamicin
Synonyms
gentamicin sulfate
Database Links
ChEMBL Ligand CHEMBL329592
DrugBank Ligand DB00798
GtoPdb PubChem SID 135650301
PubChem CID 3467
Search Google for chemical match using the InChIKey CEAZRRDELHUEMR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CEAZRRDELHUEMR
Search PubMed clinical trials gentamicin
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Search UniChem for chemical match using the InChIKey CEAZRRDELHUEMR-UHFFFAOYSA-N
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Wikipedia Gentamicin
Comments
The approved drug gentamicin is a complex of three closely-related aminoglycoside sulfates: C1, C1a and C2. The structure shown here is representative of the general structure of the compounds. For more information on the structure of the individual components of gentamicin, please see the relevant entries on ChEBI: (CHEBI:27412, CHEBI:27784, CHEBI:28292).