dofetilide

Ligand id: 2604

Name: dofetilide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 121.57
Molecular weight 441.14
XLogP 2.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1999))
IUPAC Name
N-[4-[2-[2-(4-methanesulfonamidophenyl)ethyl-methylamino]ethoxy]phenyl]methanesulfonamide
International Nonproprietary Names
INN number INN
6756 dofetilide
Synonyms
Tikosyn® | UK-68798
Database Links
BindingDB Ligand 50031720
CAS Registry No. 115256-11-6
ChEBI CHEBI:4681
ChEMBL Ligand CHEMBL473
DrugBank Ligand DB00204
GtoPdb PubChem SID 135650201
PubChem CID 71329
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Wikipedia Dofetilide
Comments
Dofetilide blocks potassium voltage-gated channels (HERGs).