triamcinolone

Ligand id: 2870

Name: triamcinolone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 115.06
Molecular weight 394.18
XLogP 0.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
755 triamcinolone
Synonyms
fluoxiprednisolone | Kenalog® | Nasacort®
Comments
Triamcinolone is a synthetic glucocorticoid anti-inflammatory drug. The approved drug is often administered in the formulation triamcinolone acetonide. Hexacetonide, furetonide and benetonide forms are also used in the clinic, and have individual INNs.
Database Links
BindingDB Ligand 41132
CAS Registry No. 124-94-7 (source: Scifinder)
ChEMBL Ligand CHEMBL1451
DrugBank Ligand DB00620
GtoPdb PubChem SID 135651276
NURSA Ligand 10.1621/K3ABSVKWO5
PubChem CID 31307
Search Google for chemical match using the InChIKey GFNANZIMVAIWHM-OBYCQNJPSA-N
Search Google for chemicals with the same backbone GFNANZIMVAIWHM
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Search UniChem for chemical match using the InChIKey GFNANZIMVAIWHM-OBYCQNJPSA-N
Search UniChem for chemicals with the same backbone GFNANZIMVAIWHM
Wikipedia Triamcinolone