fludrocortisone

Ligand Id: 2873
Ligand name fludrocortisone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 380.2
XLogP 0.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1955))
DrugBank groups approved
IUPAC Name
(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
460 fludrocortisone
Synonyms
9α-Flourocortisol
Database Links
CAS Registry No. 127-31-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1201388
DrugBank Ligand DB00687
PubChem CID 31378
Search Google for chemical match using the InChIKey AAXVEMMRQDVLJB-BULBTXNYSA-N
Search Google for chemicals with the same backbone AAXVEMMRQDVLJB
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Wikipedia Fludrocortisone
ZINC ZINC04097304
Comments
Fludrocortisone is a synthetic mineralocorticoid drug with anti-inflammatory effects.