Ligand id: 2873

Name: fludrocortisone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 380.2
XLogP 0.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Fludrocortisone may be used as hormone replacement therapy to correct adrenocortical insufficiency in Addison's disease patients.
Mechanism Of Action and Pharmacodynamic Effects
Fludrocortisone is a mineralocorticoid receptor agonist.