medroxyprogesterone

Ligand id: 2879

Name: medroxyprogesterone

Abbreviated name: MPA

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View more information in the IUPHAR Pharmacology Education Project: medroxyprogesterone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 54.37
Molecular weight 344.24
XLogP 3.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
IUPAC Name
(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
853 medroxyprogesterone
Synonyms
hydroxymethylprogesterone
Database Links
CAS Registry No. 520-85-4 (source: Scifinder)
ChEBI CHEBI:6715
ChEMBL Ligand CHEMBL1390
DrugBank Ligand DB00603
PubChem CID 10631
Search Google for chemical match using the InChIKey FRQMUZJSZHZSGN-HBNHAYAOSA-N
Search Google for chemicals with the same backbone FRQMUZJSZHZSGN
Search PubMed clinical trials medroxyprogesterone
Search PubMed titles medroxyprogesterone
Search PubMed titles/abstracts medroxyprogesterone
Search UniChem for chemical match using the InChIKey FRQMUZJSZHZSGN-HBNHAYAOSA-N
Search UniChem for chemicals with the same backbone FRQMUZJSZHZSGN
Wikipedia Medroxyprogesterone
Comments
The DrugBank entry for medroxyprogesterone shows the structure of the acetate form. Medroxyprogesterone (drug name) is the parent compound with medroxyprogesterone acetate being the active ingredient of the approved drug.