pirenzepine

Ligand id: 328

Name: pirenzepine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 68.78
Molecular weight 351.17
XLogP 1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
International Nonproprietary Names
INN number INN
3476 pirenzepine
Comments
Pirenzepine muscarinic acetylcholine receptor antagonist, selective for the M1 receptor subtype.
Database Links
BindingDB Ligand 50005675
BitterDB Ligand 676
CAS Registry No. 28797-61-7 (source: Scifinder)
ChEMBL Ligand CHEMBL9967
GtoPdb PubChem SID 135650832
PubChem CID 4848
Search Google for chemical match using the InChIKey RMHMFHUVIITRHF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RMHMFHUVIITRHF
Search PubMed clinical trials pirenzepine
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Search UniChem for chemical match using the InChIKey RMHMFHUVIITRHF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RMHMFHUVIITRHF
Wikipedia Pirenzepine