succinylcholine

Ligand id: 4004

Name: succinylcholine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 52.6
Molecular weight 290.22
XLogP -0.74
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (FDA (1952))
IUPAC Name
trimethyl[2-({4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl}oxy)ethyl]azanium
International Nonproprietary Names
INN number INN
26 suxamethonium chloride
Synonyms
Quelicin®
Comments
Succinylcholine (sux) is a short-acting depolarizing neuromuscular blocker. It acts as an acetylcholine antagonist at nicotinic acetylcholine receptors at neuromuscular junctions, resulting in persistent depolarization of the motor end plate.
Database Links
CAS Registry No. 306-40-1 (source: Scifinder)
ChEMBL Ligand CHEMBL703
DrugBank Ligand DB00202
GtoPdb PubChem SID 178100830
PubChem CID 5314
RCSB PDB Ligand SCK
Search Google for chemical match using the InChIKey AXOIZCJOOAYSMI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AXOIZCJOOAYSMI
Search PubMed clinical trials suxamethonium chloride
Search PubMed titles suxamethonium chloride
Search PubMed titles/abstracts suxamethonium chloride
Search UniChem for chemical match using the InChIKey AXOIZCJOOAYSMI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone AXOIZCJOOAYSMI
Wikipedia Suxamethonium_chloride