succinylcholine

Ligand id: 4004

Name: succinylcholine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 52.6
Molecular weight 290.22
XLogP -0.74
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Skeletal muscle relaxant used in surgical procedures where a rapid onset and brief duration of muscle relaxation is required.
Mechanism Of Action and Pharmacodynamic Effects
Succinylcholine mimics the effects of acetylcholine but without being rapidly hydrolysed by acetylcholinesterase, leading to persistent depolarisation of the neuromuscular junction leading to desensitisation.
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