metformin

Ligand id: 4779

Name: metformin

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: metformin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 91.49
Molecular weight 129.1
XLogP -0.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
IUPAC Name
1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide
International Nonproprietary Names
INN number INN
965 metformin
Synonyms
Glucophage® | LA-6023
Database Links
CAS Registry No. 657-24-9
ChEBI CHEBI:6801
ChEMBL Ligand CHEMBL1431
DrugBank Ligand DB00331
PubChem CID 4091
RCSB PDB Ligand MF8
Search Google for chemical match using the InChIKey XZWYZXLIPXDOLR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XZWYZXLIPXDOLR
Search PubMed clinical trials metformin
Search PubMed titles metformin
Search PubMed titles/abstracts metformin
Search UniChem for chemical match using the InChIKey XZWYZXLIPXDOLR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XZWYZXLIPXDOLR
Wikipedia Metformin
Comments
Marketed formulations contain metformin hydrochloride (PubChem CID 14219). Metformin is often given in fixed-dose combinations with other antihyperglycemic agents.