ketoprofen

Ligand id: 4795

Name: ketoprofen

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View more information in the IUPHAR Pharmacology Education Project: ketoprofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 54.37
Molecular weight 254.09
XLogP 4.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1986))
IUPAC Name
2-(3-benzoylphenyl)propanoic acid
International Nonproprietary Names
INN number INN
3284 ketoprofen
Synonyms
Actron® | Orudis®
Database Links
CAS Registry No. 22071-15-4 (source: Scifinder)
ChEBI CHEBI:6128
ChEMBL Ligand CHEMBL571
DrugBank Ligand DB01009
GtoPdb PubChem SID 178101497
PubChem CID 3825
Search Google for chemical match using the InChIKey DKYWVDODHFEZIM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DKYWVDODHFEZIM
Search PubMed clinical trials ketoprofen
Search PubMed titles ketoprofen
Search PubMed titles/abstracts ketoprofen
Search UniChem for chemical match using the InChIKey DKYWVDODHFEZIM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DKYWVDODHFEZIM
Wikipedia Ketoprofen
Comments
The approved drug ketoprofen is a mixture of two stereoisomers; an (R)-enantiomer (see PubChem CID 180540), and an (S)-enantiomer (see PubChem CID 667550), with only the (S)-enantiomer possessing biological activity. The structure shown here does not specify stereochemistry and represents the mixture of isomers.