ketoprofen

Ligand id: 4795

Name: ketoprofen

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View more information in the IUPHAR Pharmacology Education Project: ketoprofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 54.37
Molecular weight 254.09
XLogP 4.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
Mechanism Of Action and Pharmacodynamic Effects
Ketoprofen is a non-selective COX ennzyme inhibitor. For an overview of the mechanism of action of ketoprofen, please see the DrugBank link on the Summary tab of this ligand page.