chlorothiazide

Ligand Id: 4835
Ligand name chlorothiazide

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 135.45
Molecular weight 294.95
XLogP -0.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1958))
DrugBank groups Approved
IUPAC Name
6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
International Nonproprietary Names
INN number INN
636 chlorothiazide
Database Links
CAS Registry No. 58-94-6 (source: Scifinder)
ChEMBL Ligand CHEMBL842
DrugBank Ligand DB00880
PubChem CID 2720
Search Google for chemical match using the InChIKey JBMKAUGHUNFTOL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JBMKAUGHUNFTOL
Search PubMed clinical trials chlorothiazide
Search PubMed titles chlorothiazide
Search PubMed titles/abstracts chlorothiazide
Wikipedia Chlorothiazide
ZINC ZINC03872055
Comments
Chlorothiazide is thiazide diuretic, similar to hydrochlorothiazide.